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Independent GLP-1 Testing · Elyria, Ohio

Semaglutide, tested by an independent U.S. lab.

More semaglutide is copied than any other peptide sold into this market, which is the awkward thing about accepting a certificate from the same company that sold you the vial. Erie Coast Analytical holds no vendor relationships and takes no commission on anything it tests, so we have nothing to protect by grading generously. We test the vial you actually received and report what the instrument produced, whether that helps your supplier or not. Identity, quantity, and purity are included in the base test. Endotoxin testing, sterility testing, and heavy metals testing are available as optional add-ons.

$195.00 per sample · signed COA

How a sample becomes
a certificate.

Every semaglutide sample moves through the same five steps. No shortcuts for rush orders. No unnamed hands in the middle.

Intake.

Your sample arrives. We photograph it, weigh it, log every detail, and assign a tracking number that follows it onto every page.

Prep.

A named analyst prepares the run: dissolutions, dilutions, internal standards. Their initials go in the log.

Run.

HPLC-UV for purity, LC-MS for identity, and quantitative analysis for the amount present, with system-suitability standards bracketing your sample on either side.

Review.

A second analyst reviews the chromatogram independently. Nothing ships with one set of eyes on it.

Sign.

The COA is digitally signed, hashed, and published. Anyone with the link can verify the signature against the raw data.

What we look for

What we look for in semaglutide

Which GLP-1 it actually is.

Semaglutide, liraglutide and tirzepatide are sold into the same market and confused constantly. Each has its own mass. One LC-MS run tells them apart.

The linker and the side chain.

Incomplete coupling leaves molecules that are close to right and lighter than expected. Purity alone will not flag them; mass will.

Fill weight against the label.

A vial can show high percent-area purity and still contain less material than its label states. Quantity is included in the base test and reported separately from purity.

What you receive

Paper you can stake a reputation on.

01

A signed Certificate of Analysis

Identity, quantity, and purity on one document, signed by the director, not a template stamp.

02

Method-level transparency

Column, wavelength, ionization mode, and acceptance criteria are stated, not implied.

03

Public verification

Each COA carries a hash and signature anyone can check at our verify endpoint, on or off our site.

Frequently asked

Semaglutide testing, answered.

Does ECA test semaglutide samples?+
Yes. Semaglutide is one of the most frequently submitted compounds in our catalog. Identity is confirmed by LC-MS intact mass, quantity is measured, and purity is reported by HPLC-UV as percent area. The results are issued on a signed Certificate of Analysis.
Is semaglutide testing performed in the United States?+
Yes. All analysis is performed in-house at our laboratory in Elyria, Ohio. We are an independent U.S. lab. We don't outsource testing or ship samples overseas, and every result is produced and signed by our own analysts.
What does the semaglutide Certificate of Analysis include?+
A completed semaglutide COA documents identity by intact-mass LC-MS, the measured quantity, HPLC-UV purity as percent area, the method parameters used, and the analyst and director who signed off. It is digitally signed and independently verifiable.
How long does semaglutide testing take?+
Typical turnaround is 24-48 hours from the day your sample is received at the lab. You'll get shipping instructions, a packing slip, and labels after checkout.
What methods are used for semaglutide identity, quantity, and purity?+
Identity is confirmed by LC-MS intact-mass analysis. Quantity is measured and reported separately from percent-area purity. Purity is measured by reversed-phase HPLC-UV and reported as percent area.
My vendor already sent a COA. Why test again?+
A certificate is only as independent as the lab that signed it. Many vendor COAs are issued by the manufacturer, reused across batches, or carry no verifiable signature at all. We have no relationship with any vendor, we test the vial you actually received, and every certificate we issue can be checked against our records by anyone you show it to.
Is this medical or dosing advice?+
No. ECA provides analytical testing for research compounds only. We do not provide medical advice, dosing guidance, treatment claims, or clinical evaluation of any kind.
Erie Coast Analytical provides analytical testing services for research compounds and does not provide medical advice, dosing guidance, treatment claims, or clinical evaluation. Endotoxin testing, sterility testing, and heavy metals testing are available as optional add-ons. The interactive catalog remains the source of truth for current availability, checkout pricing, and add-on testing panels.